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Prerequisites:
BIOL 302 (Molecular and General Genetics) and BIOL 303 (Cell Biology)
or equivalent courses with a grade of C or better are required.
From these courses, students are expected to have mastered the basic
concepts of bacterial genetics and molecular biology. The
relevant material is covered in Chapters 10-18 and 20-23 of Principles
of Genetics, 3rd Edition by Snustad and Simmons, and in Chapters
2-7, 14, 16-17, and 19 of iGenetics by Russell, the texts
used in BIOL 302 the past few years.
Text:
No text is required. Instead, readings from the scientific literature
will be assigned for each class period. Students should make their
own copies of the papers and bring them to class. In addition, it
would be useful to have an introductory genetics text available.
Grading:
- Class participation (including quizzes): 30%
- Mid-term Exam (Thurs., March 25, 9:00 am): 30%
- Written critique of journal article due Thurs, April 29): 10%*
- Final Exam (Thurs., May 18, 10:30 am- 12:30 pm): 30%
Exam grades are usually curved and 5 points will be added to the
scores of the BIOL 434 students after the curve has been set.
*The writing assignment is optional.
For those who choose not to do it, the exams will each count 35%
of the final grade and class participation will remain at 30% of
the final grade.
Class Participation: One to two papers will be covered each
class period, with different students answering the questions about
background, objective, methods, results, and conclusions. These
randomly chosen participants will be graded as follows:
- A, for an excellent answer;
- B, for a generally correct answer;
- C, for a reasonable effort when the main point was missed;
- D, for no answer, or when the student has failed to read the
paper;
- F, for a student who is absent when called on.
In addition,
extra credit is given for a voluntary correct answer, with 3 such
answers equal to an A when called on at-random.
Written Critique of Journal Article:
Students will choose from a list of papers. Students enrolled in BIOL
434 and BIOL 634 will have different lists of papers. The format for
the critique is similar to the analysis of the papers covered in class.
Specific instructions will be provided
at a later date. As mentioned above, this assignment is optional;
omitting it increases the relative value of each exam by 5%. The
list of papers will be provided before spring break.
Assigned Readings:
The papers are available on the Readings
page of this site and within the Schedule;
they may be printed out from within your browser with Adobe
Acrobat Reader. A password to enable access to the pdf files will
be given in class. Copies of mid-term exams from previous years may
be accessed from the library's electronic
reserves internet site; the necessary username and password will
be provided in class.
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