D. M. Strauss, S. Lute, Z. Tebaykina, D. D. Frey, C. Ho, S. G. Blank, K. Brorson, Q. Chen, B. Yang, "Understanding the Mechanism of Virus Removal by Q Sepharose Fast Flow Chromatography During the Purification of CHO-Cell Derived Biotherapeutics, " Biotechnol. Bioeng. 104, 371-380, 2009.  [abstract]

H. Shen, D. D. Frey, "Serial Displacement Chromatofocusing and its Applications in Multidimensional Chromatography and Gel Electrophoresis: Part I. Theory and General Considerations," J. Chromatogr. A, 1216, 967-976, 2009.  [abstract]

H. Shen, X. Li, C. J. Bieberich, D. D. Frey, "Serial Displacement Chromatofocusing and its Applications in Multidimensional Chromatography and Gel Electrophoresis: Part II. Experimental Results," J. Chromatogr. A, 1216, 977-986, 2009.  [abstract]

K. Brorson, H. Shen, S. Lute, J. Soto Pérez, D. D. Frey, "Characterization and Purification of Bacteriophages Using Chromatofocusing," J. Chromatogr. A, 1207, 110-121, 2008. [abstract]

H. Shen, X. Li, C. J. Bieberich, D. D. Frey, "Reducing Sample Complexity in Proteomics by Chromatofocusing with Simple Buffer Mixtures," Methods. Mol. Biol., 424, 187-203, 2007. [abstract]

X. Ge, M. Hanson, H. Shen, Y. Kostov, K.A. Brorson, D. D. Frey, A. R. Moreria, G. Rao, " Validation of an Optical Sensor-Based High-Throughput Bioreactor System for Mammalian Cell Culture," J. Biotechnol., 22, 293-306, 2006. [abstract]

D. D. Frey, X. Kang, "New Concepts in the Chromatography of Peptides and Proteins," Curr. Opin. Biotechnol., 16, 552-560, 2005. [abstract]

J. Soto Pérez, D. D. Frey, "Behavior of the Inadvertant pH Transient Formed by a Salt Gradient in the Ion-Exchange Chromatography of Proteins," Biotechnol. Progr., 21, 902-910, 2005. [abstract]

H. Shen, D. D. Frey, "Effect of Charge Regulation on Steric Mass-Action Equilibrium for the Ion-Exchange Adsorption of Proteins," J. Chromatogr. A, 1079, 92-104, 2005. [abstract]

X. Kang, D. D. Frey, "Chromatofocusing of Peptides and Proteins Using Linear pH Gradients Formed on Strong Ion-Exchange Adsorbents," Biotechnol. Bioeng., 87, 376-387, 2004. [abstract] 

H. Shen, D. D. Frey, "Charge Regulation in Protein Ion-Exchange Chromatography: Development and Experimental Evaluation of a Theory Based on Hydrogen Ion Donnan Equilibrium," J. Chromatogr. A, 1034, 55-68, 2004. [abstract]  

X. Kang, D. D. Frey, "High-Performance Cation-Exchange Chromatofocusing of Proteins,"  J. Chromatogr. A, 991, 117-128, 2003. [abstract] 

X. Kang, D. D. Frey, "Chromatofocusing Using Micropellicular Column Packings with Computer-Aided Design of the Elution Buffer Composition," Anal. Chem., 74, 1038-1045, 2002. [abstract] 

D. D. Frey, C. R. Narahari, C. D. Butler, "General Local-Equilibrium Chromatographic Theory for Eluents Containing Adsorbing Buffers," AIChE J., 48, 561-571, 2002. [abstract]

D. Farnan, D. D. Frey, Cs. Horváth, "Surface and Pore Diffusion in Macroporous and Gel-Filled Gigaporous Stationary Phases for Protein Chromatography," J. Chromatogr. A, 959, 65-73, 2002. [abstract]

D. D. Frey, R. C. Bates, C. Narahari, "Chromatofocusing" in Encyclopedia of Life Sciences, McMillan Publishers, 2001 [abstract] 

C. R. Narahari, L. Randers-Eichhorn, J. C. Strong, N. Ramasubramanyan, G. Rao, D. D. Frey, "Purification of Recombinant Green Fluorescent Protein Using Chromatofocusing with a pH Gradient Composed of Multiple Stepwise Fronts," Biotechnol. Prog., 17, 150-160, 2001 [abstract]

R. Bates, X. Kang, D. D. Frey, "High Performance Chromatofocusing Using Linear and Concave pH Gradients Formed with Simple Buffer Mixtures  I. Effect of Buffer Composition on the Gradient Shape,"  J. Chromatogr. A, 890, 25-36, 2000.  [abstract]

X. Kang, R. Bates, D. D. Frey, "High Performance Chromatofocusing Using Linear and Concave pH Gradients Formed with Simple Buffer Mixtures  II. Separation of Proteins," J. Chromatogr. A, 890, 37-43, 2000.  [abstract]