© 2000-2008 Ingenuity Systems, Inc. All rights reserved. List -log(p-value) Ratio Molecules Hepatic Stellate Cell Activation 2.19E00 8.57E-02 CCL2,TGFBR3,TGFB3 VDR/RXR Activation 2E00 5.19E-02 SERPINB1,KLF4,PRKCA,PRKCB1 FXR/RXR Activation 1.94E00 5E-02 BAAT,MLXIPL,CYP19A1,PPARGC1A Hepatic Fibrosis 1.85E00 4.71E-02 TIMP3,CCL2,LUM,TGFB3 PPARα/RXR Activation 1.43E00 2.98E-02 RELB,TGFB3,PPARGC1A,PRKCA,PRKCB1 Hypoxia-Inducible Factor Signaling 1.38E00 4.29E-02 UBE2J1,PRKCA,PRKCB1 Cytochrome P450 Panel - Substrate is an Eicosanoid (Mouse) 1.19E00 1.67E-01 PTGIS Cytochrome P450 Panel - Substrate is an Eicosanoid (Human) 1.13E00 1.43E-01 PTGIS Mechanism of Gene Regulation by Peroxisome Proliferators via PPARα 1.06E00 3.16E-02 PPARGC1A,PRKCA,PRKCB1 Cytochrome P450 Panel - Substrate is a Fatty Acid (Human) 9.82E-01 1E-01 PTGIS Cytochrome P450 Panel - Substrate is a Sterol (Human) 8.45E-01 7.14E-02 CYP19A1 Cytochrome P450 Panel - Substrate is a Sterol (Mouse) 8.45E-01 7.14E-02 CYP19A1 Cytochrome P450 Panel - Substrate is a Sterol (Rat) 8.45E-01 7.14E-02 CYP19A1 LXR/RXR Activation 7.58E-01 2.9E-02 CCL2,RELB Hepatic Cholestasis 7.34E-01 2.22E-02 RELB,PRKCA,PRKCB1 Aryl Hydrocarbon Receptor Signaling 6.28E-01 1.96E-02 GSTM5,TGFB3,ALDH18A1 Oxidative Stress Response Mediated by Nrf2 4.09E-01 1.46E-02 GSTM5,PRKCA,PRKCB1 Xenobiotic Metabolism 3.83E-01 1.55E-02 GSTM5,CYP19A1 G1/S Transition of the Cell Cycle 3.73E-01 2E-02 TGFB3 Oxidative Stress 3.31E-01 1.75E-02 GSTM5 TGF-β Signaling 2.42E-01 1.3E-02 TGFB3