| CHEM 644/444 - Molecular Modeling in Biochemistry |
| Fall Semester, 2005 |
Instructor: C. Allen Bush -
ext. 5-2506 - bush@umbc.edu
For syllabus and further information see
Website:
http://www.gl.umbc.edu/ ~ bush/course/ch644/ch644.html
Molecular Modeling in Biochemistry ( 2 hr lecture + 2 hr lab, total 3 credit hr)
Prerequisites: CHEM 437 and CHEM 301 (or 303) or equivalent or permission of the instructor.
Survey of theoretical methods for simulation of biopolymer conformation. Force fields, energy maps, energy minimization, and molecular dynamics simulation. Influence of solvent. Applications to proteins, nucleic acids and polysaccharides. Laboratory section will emphasize practical calculations on biopolymers and use of data bases of structural biochemistry.
The laboratory provides hands-on computer experience with Unix workstations including Silicon Graphics and Linux computers to supplement the lecture material. This course will serve as an advanced elective course for students of both the Chemistry and of the Biochemistry undergraduate programs as well as for students of the Ph.D programs in Chemistry and Biochemistry.
Laboratory section: Tues. 9 AM- 11 AM
Lecture section: Thurs. 9 AM- 11 AM