Yonghyun (John) Kim

Yonghyun (John) Kim, PhD
yk1 [at] umbc [dot] edu
Class of 2008
Chemical and Biochemical Engineering
University of Maryland, Baltimore County (UMBC)*
* Currently at The University of Alabama

Research Interest (2002-2008):

My research interest is in characterizing global molecular and physiological events of microbial systems via systems biological approach. I'm a member of Dr. Mark R. Marten's Group, where our system of choice is Aspergillus nidulans and other relevant and beneficial filamentous fungi. Our main tool of analysis is comparative proteomics via two-dimensional gel electrophoresis and mass spectrometric identification of proteins of interest, through which we not only acquire a panoptic snapshot of functional-level changes in the cells, but also assign probable functions to novel and/or hypothetical proteins. The biological question we are currently addressing is how fungi adapt to stressful conditions, including conditions of elevated salt concentration, carbon-starvation, and the presence of antibiotics.

A.nidulans 2DE pI 4-7
Aspergillus nidulans wildtype intracellular 2DE proteome map
(pI 4-7, Mr 15-200 kDa)

A.nidulans 2DE pI 3-11 NL
Aspergillus nidulans mutant intracellular 2DE proteome map
(pI 3-11 NL, Mr 15-200 kDa)

Selected Publications:

6.  Klionsky DJ et al. (2012) Autophagy, "Guidelines for the use and interpretation of assays for monitoring autophagy" [Pubmed]

5.  Kim Y*, Islam N, Moss BJ, Nandakumar MP, Marten MR (2011) Biotechnol Bioeng, "Autophagy induced by rapamycin and carbon-starvation have distinct proteome profiles in Aspergillus." (* corresponding) [Pubmed]

4.  Kim Y, Nandakumar MP, Marten MR (2008) Brief Func Genom Proteom, "The state of proteome profiling in the fungal genus Aspergillus." [Pubmed]

3.  Moss BJ, Kim Y, Nandakumar MP, Marten MR (2008) Biotechnol Prog, "Quantifying metabolic activity of filamentous fungi using a colorimetric XTT assay." [Pubmed]

2.  Kim Y, Nandakumar MP, Marten MR (2007) Trends in Biotechnol, "Proteomics of filamentous fungi." [Pubmed]

1.  Kim Y, Nandakumar MP, Marten MR (2007) Fungal Genet and Biol, "Proteome map of Aspergillus nidulans during osmoadaptation." [Pubmed]

Full List of Publications:

Publications list Yonghyun Kim