Welcome! This page includes some refrences about continuous fermentation, Microbiology and bioreactors in the literature.

Fed-batch Systems

 

	Bosnjak, M., V. Topolovec, and V. Johanides, (1979) "Growth Kinetics and Antibiotic Synthesis during the Repeated Fed-batch Culture of Streptomyces", Biotechnol. Bioengr. Symp.9, 155-165
	Fan-Chiang Yang, Der-Wei Maa, "Fed-batch culture of yeast Saccharomyces cerevisiae with a DO-stat method by a fuzzy controller", Bioprocess Engineering, Volume 18 Issue 2 (1998) pp 79-82
	H. S. Kim, J. Y. Ju, J. H. Suh, C. S. Shin, "Optimized fed-batch fermentation of L-<beta>-hydroxy isobutyric acid by Yarrowia lipolytica", Engineering, Volume 20 Issue 3 (1999) pp 189-193

Continuous Fermentation

 

	M. Rutgers, Daniel D. Gooch, Anton M. Breure, Johan G. Van Andel, "Assessment of inhibition kinetics of the growth of strain P5 on pentachlorophenol under steady-state conditions in a nutristat", Archives of Microbiology, Volume 165 Issue 3 (1996) pp 194-200
	Markx, G.H., Davey, C.L. & Kell, D.B. (1991) The permittistat: a novel type of turbidostat. J. Gen. Microbiol., 137, 735-743. [Control of cell growth in a turbidostat based on the Biomass Monitor]
	JAROSLAV  FLEGR , "Two distinct types of natural selection in turbidostat-like and chemostat-like ecosystems", J.theor.Biol. 1997 188: 121-126
	Biebl, H. (1991) Glycerol fermentation of 1,3-propanediol by Clostridium butyricum - measurement of product inhibition by use of a pH-auxostat. Applied Microbiology And Biotechnology, 35, 701-705.
	Bryson, V. (1952) Part II: The turbidostatic selector-a device for automatic isolation of bacterial variants. Science, 116, 48-51.
	Fraleigh, S. P., Bungay, H. R., Clesceri, L. S. (1989) Continuous culture, feedback control and auxostats. Trends in Biotechnol. 7, 159-164
	Konstantinov, K., Kishimoto, M., Seki, T., and Yoshida, T. (1990) A balanced DO-stat and its applications to the control of acetic acid excretion by combinant, Escherichia coli. Biotech. Bioeng., 36, 750-758
	Larsson, G., Enfors, S.O., and Pham, H. (1990) The pH-auxostat as a tool for studying microbial dynamics in continuous fermentation. Biotech. Bioeng., 36,224-232.
	Lin, Y-H., and Bungay, H.R. (1993) Rapid microbial growth in a pH auxostat. Biotechnol. Techniques, 7,(2) 127-130
	Minkevitch, I.G., Krynitskaya, and Eroshin, V.K. (1989) Bistat - a novel method of continuous cultivation. Biotech. Bioeng., 33, 1157-1161.
	Mormino, R., and Bungay, H. (1993) Specific gravity as an auxostat control variable. Biotechnol. Techniques, 7:(3) 229-230
	Rice, C.W., and Hempfling, W.P. (1985) Nutrient limited growth in the pHauxostat. Biotechnol. Bioeng., 27, 187-191.
	Yamada, S., Wada, M., and Chibata, I. (1979) Oxygen transfer as a parameter of automatic control of the continuous cultivation for the conversion of sorbitol to sorbose by Acetobacter suboxydans. J. Ferment. Technol., 57, 210-214.
	Mü hlemann, M., and Bungay, H. (1993) An ethanol auxostat with on-line gas sensing. Biotechnology Techniques, 7, 575-578

Growth and Models

 

	J.F. Andrews, "A mathematical model for continuous culture of microorganisms using inhibitory substrates", Biotechnol Bioengr. 10: 707-723 (1968)
	Peringer, P., and H.T. Blanchere, (1979) "Modeling and Optimal Control of Bakers' Yeast Production in Repeated Fed-batch Culture", Biotechnol. Bioengr. Symp. 9, 205-213
	Fredrickson, A.G., Megee, R.D. and Tsuchiya, H.M. (1970) Mathematical models for fermentation processes. Adv. Appl. Microbiol., 13, 19-465.

Last modify: 03/20/2000