Thesis working title:  Cell- Cell, Virus-Cell infection during HIV and T-cell Activation

The human immunodeficiency virus (HIV) was discovered in 1983, and twenty five years later the lack of complete understanding of the disease remains questioned. We have been working on developing a mathematical model for HIV infection based on two infection mechanism free floating virions and cell to cell transmission.  

Some of questions that Joe thinks about: Can I predict strains that will not be infectious? How important is recombination to HIV replication? How can I distinguish one drug regimen from another mathematically?

Presentations

Piekarski and M.Castellanos, Modeling HIV through two distinct pathways, Look Ahead XI. Poster. UMBC, November 2007.

J. McGill, J. Piekarski and M. Castellanos, Modeling Viral Kinetics. Poster. Wyeth Summit, UMBC, August 2007.