Investigating Strategies and Research Methods To Prevent Staphylococcus aureus Infections
Topic
WWW Links
References
Relevance-Why Important Staphylococci-The Emerging Threat
Support of emerging antibiotic resistance.
http://ci.mond.org/9506/950608.html
Rubin, R., Harrington, C., Poon, A., Dietrich, K., Greene, J., and Moiduddin, A. 1999. "The economic impact of Staphylococcus aureus infection in New York City Hospitals", Emerging Infectious Diseases.  5:1.
  The Challange of Antibiotic Resistance
Support of emerging antibiotic resistance.
http://www.sciam.com/1998/0398issue/0398levy.html#links
Henderson, D.  1997. "Healthcare institutions as 'hot zones': emerging and re-emerging pathogens", Current Opinion in Infectious Diseases. 10:310-318.
Drug Resistance
A very basic explanation of drug resistance.
http://www.drhull.com/EncyMaster/R/resistance_drug.html
L. Mounthon and Dr. Jean-Luc Mainardi, 1996.  "Vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus: the Gram-positive challanges", Current Opinion in Infectious Diseases.  9:256-260.
Bacterial Invasion Mechanisms Colonization vs Infection
Explanation of bacterial invasion.
http://www.springnet.com/ce/p609as02.htm
Sullam, P. 1994. "Host-pathogen interactions in the development of bacterial endocarditis", Current Opinion in Infectious Diseases. 7:304-309.
  Colonization and Invasion
Great explanation of bacterial invasion to host tissue.
http://www.bact.wisc.edu/microtextbook/disease/
colinize.html
Foster, T.J. and McDevitt, D.  1994.  “Surface-associated proteins of Staphylococcus aureus:  Their possible roles in virulence”, FEMS Microbiology Letter. 118:  199-206.
Host Parasite Interactions
Explanation of colonization and invasion of bacteria.
http://xena.lsb.sbs.auckland.ac.nz/~pmetcalf/405.352/
general/uwisc/Bact330/lecturecolin.html
Switalski, L., Patti, J., Butcher, W., Gristina, A., Speziale, P., and Hook, M.  1993.  “A collagen receptor on Staphylococcus aureus strains isolated from patients with septic arthritis mediates adhesion to cartilage”, Molecular Microbiology.  7(1):  99-107.
Staphylococcus aureus Information Staphylococcus-Timothy Foster
General information about Staph.
http://gsbs.utmb.edu/microbook/ch012.htm
Clements, M. 1999. "Stress resistance in Staphylococcus aureus", Trends in Microbiology. 7:11:458-462.
  Microbiology:  Bacteriology-Staphylococcus
General information about Staph.
http://www.kumc.edu/AMA-MSS/study/
micro3.htm#staphylococci
Tarkowski, A. and Wagner, H. 1998. "Arthritis and sepsis caused by Staphylococcus aureus: can teh tissue injury be reduced by modulating the host's immune system?', Molecular Medicine Today.  4:I:15-18.
Staphylococcal Infections
General information about Staph. infections.
http://www.slis.ua.edu/cdlp/WebCoreAll/patientinfo/infectious/
staphylococcal.htm
Watanakunakorn, C.  1996. "Staphylococcal endocarditis", Current Opinion in Infectious Diseases. 9:105-108.
Extra Cellular Matrix  Serves as Surface Adhesion Tissue Dr. Joseph Patti
Researcher in bacterial adhesion to ECM proteins.
http://www-ibt.tamu.edu/ibt/pr/ibtweb/faculty.htm#Patti
Foster, T. and Hook, M.  1998. "Surface protein adhesins of Staphylococcus aureus", Trends in Microbiology. 6:12:484-488.
  Dr. Magnus Hook
Researcher in bacterial adhesion to ECM proteins.
http://www-ibt.tamu.edu/ibt/pr/ibtweb/mh.html
Patti, J. and Hook, M.  1994. "Microbial adhesins recognizing extracellular matrix macromolecules", Current Opinion in Cell Biology.  6:752-758.
  Bacterial Surface Proteins
Good page on collagen (with receptor model) and fibrinogen.
http://www.cmc.uab.edu/faculty_staff/narayana/bacterial.html
Speziale, P., Raucci, G., Visai, L., Switalski, L., Timpl, R., and Hook, M. 1986.  “Binding of Collagen to Staphylococcus aureus Cowan 1”, Journal of Bacteriology.  167:  77-81
  Extracellular Matrix
Short explanation of ECM and it's proteins.
http://www.hsc.usf.edu/~pneame/ecm.html
Fibronectin
Information on fibronectin-structure in ECM.
http://www.teaching-biomed.man.ac.uk/lawson/Fibronec.HTM
Dynamic Bacterial Adhesion Dr. Julie Ross
Researcher in dynamic adhesion field
http://umbc7.umbc.edu/~jross/index.htm
Dickinson, R. and Cooper, S.  1995.  “Analysis of Shear-Dependent Bacterial Adhesion Kinetics to Biomaterial Surfaces”,  AIChE Journal.  41(9): 2160-2173.
  Dr. Douglas A. Lauffenburger
Researcher in dynamic adhesion field.
http://web.mit.edu/beh/people/lauf.htm
Hammer, D. and Apte, S.  1992.  “Simulation of cell rolling and adhesion on surfaces in shear flow:  general results and analysis of seletin-mediated neutrophil adhesion”, Biophys. J.  63:  35-57.
  Dr. Daniel Hammer
Researcher in dynamic adhesion field.
http://www.seas.upenn.edu/cheme/hammer.html
Cozens-Roberts, C., Lauffenburger, D., and Quinn, J.  1990. “Receptor-mediated cell attachment and detachment kinetics II:  Experimental model studies with the Radial-Flow Detachment Assay”,  Biophys. J.  58:  857-871.
  Dr. Richard Dickinson
Researcher in dynamic adhesion field.
http://myprofile.cos.com/dickinsr71
 
  Rolling Adhesion of Cells
Related research in the area of bacterial dynamic adhesion.
http://www.rndsystems.com/cb/cbsu95/cbsu95a2.html
 
  Dynamic Flow Assay in Flow Chamber
Protocol for dynamic bacterial adhesion assay.
http://www.rndsystems.com/cb/cbsu95/cbsu95a2.html
 
Strategies to Block Bacterial Adhesion Adhesins as Targets for Vaccine Development
Additional information on prevention strategies.
http://www.cdc.gov/ncidod/eid/vol5no3/wizeman.htm
Jan-Ingmar Flock, 1999. "Extracellular-matrix-proteins as targets fro the prevention of Staphylococcus aureus infections", Molecular Medicine Today.  5:12:532-537
  Cell Attachment Inhibition
Use of short peptide to inhibit cell attachment-protocol 
development for inhibition strategies.
http://www.lifetech.com/cgi-online/
techonline?Document=ecm.txt.4
Mohamed, N., Teeters, M., Patti, J., Hook, M., and Ross, J.  1998.  “Inhibition of Staphylococcus aureus Adherence to Collagen under Dynamic Condtions”, Infection and Immunity.  67(2):  589-594.
Antibody Information
This site explains general antibody terminology.
http://esg-www.mit.edu:8001/bio/imm/monoclonal.html
Lee, J.  1998. "An experimental vaccine that targets staphylococcal virluence", Trends in Microbiology. 6:12:461-463.
Searchable Related Databases List of Bacterial Infections and Mycosis Links
Lots of related sites that are general topics.
http://www.mic.ki.se/Diseases/c1.html
 
  Biosites
Searchable Database
http://www.library.ucsf.edu/biosites/
 
  The Bio Netbook Guide
Searchable database in related fields.
http://www.pasteur.fr/recherche/BNB/english/
guide.html#bio
 
  Biomedical Engineering Links
Related links in biomedical engineerging.
http://www.scicentral.com/E-bioeng.html