Fabris' Research Interests
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Investigation of protein-nucleic acids interactions in viruses responsible for infectious diseases.
Development of MS3D methods for structural determination of macromolecular complexes from spatial constrains provided by chemical probes and high resolution mass spectrometry.
Top-down methods for the characterization of modified proteins and nucleic acids produced by chemical probes and crosslinking techniques.
Identification of the determinants of molecular recognition in the complex between NC protein and Psi- RNA in HIV-1.
Effects of covalent adducts and ligand binding on protein-nucleic acids interactions in HIV-1 and other retroviruses. |