Our goal is to understand N-Methyl-D- Aspartate receptor (NMDAR) signaling via nitric oxide and mechanisms of glucose transporter 3 trafficking. I received basic training in Biochemistry at Albert Einstein School of Medicine under the mentorship of Dr. Ian Willis. During my postdoctoral stint at NYU School, I study NMDAR mutants and excitotoxicity with Dr. Edward Ziff. The discoveries lead to my studies of phosphorylation of nNOS. At Johns Hopkins, I began the study on NMDAR mediated regulation of surface GLUT3. Despite significant progress in our understanding of membrane trafficking in general, very little is known about the secretory and endocytic trafficking of GLUT3 in neuronal dendrites and at synapses. Our work begins to characterize the role of NO in the mechanism by which NMDAR regulates the expression of surface GLUT3 and glucose transport, a molecular correlate of cellular viability.